Glossary entry (derived from question below)
Spanish term or phrase:
necrosis comedociana
English translation:
comedo necrosis
Added to glossary by
liz askew
Nov 6, 2022 21:07
1 yr ago
22 viewers *
Spanish term
Also an Engineer
Native in: Spanish (Variant: Venezuelan)
Works in: English to Spanish, Spanish to English, Spanish
necrosis comedociana
Spanish to English
Medical
Medical (general)
prostate cancer
Estoy traduciendo unos informes médicos de un paciente con ADC de próstata. En los resultados del ecosonograma renal y vesical dice:
"Fecha xx. Hidronefrosis grado III derecha y grado II izquierda, próstata xx gramos con cambios inflamatorios y neoproliferativo infiltrativos vesicales y periprostáticos.
Fecha xxx. Biopsia #xxx. ADC próstata Gleason 8 (3+5) grupo 4 OMS severa anaplasia **necrosis comedociana** en el 10 % infiltración perineural multifocal 70 % de los fragmentos.
Un millón de gracias
"Fecha xx. Hidronefrosis grado III derecha y grado II izquierda, próstata xx gramos con cambios inflamatorios y neoproliferativo infiltrativos vesicales y periprostáticos.
Fecha xxx. Biopsia #xxx. ADC próstata Gleason 8 (3+5) grupo 4 OMS severa anaplasia **necrosis comedociana** en el 10 % infiltración perineural multifocal 70 % de los fragmentos.
Un millón de gracias
Proposed translations
(English)
| 3 +1 | comedo necrosis |
liz askew
|
| 4 | typo: necrosis coledociana / Choledochal necrosis (choledochal=biliary tract) |
Erzsébet Czopyk
|
Change log
Nov 10, 2022 12:29: liz askew Created KOG entry
Proposed translations
+1
1 hr
Selected
comedo necrosis
Cribriform Patterned Lesions in the Prostate Gland with ... - MDPI
https://www.mdpi.com › pdf
by M Destouni · 2022 — Gleason Grade of 4 (or 5 when comedo necrosis is present) [33], whereas GUPS does not support IDC incorporation in Gleason Score/PGG and ...
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Note added at 1 hr (2022-11-06 23:01:38 GMT)
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Prostate cancer with comedonecrosis is frequently, but not ...
https://pubmed.ncbi.nlm.nih.gov › ...
by R Madan · 2019 · Cited by 18 — Abstract. Aims: Comedonecrosis in prostate cancer has always been Gleason pattern 5. However, we aimed to evaluate how intraductal carcinoma
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Note added at 1 day 12 hrs (2022-11-08 09:42:44 GMT)
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Grade Group 4
Gleason score 4 + 4 = 8; 3 + 5 = 8; 5 + 3 = 8
Only poorly-formed/fused/cribriform glands;
Predominantly well-formed glands with a few areas lacking glands (or with comedonecrosis);
Predominantly lacking glands (or with comedonecrosis) and a few well-formed glands
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Note added at 1 day 12 hrs (2022-11-08 09:46:10 GMT)
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Intraductal Carcinoma of the Prostate
https://www.path.org.uk › 2018/07 › PR-2-Varma
by M Varma — Gleason score 4 + 4 = 8? ... 3. Invasive carcinoma? HMWCK. Intraductal prostate cancer ... 3 + 4**** invasive with comedonecrosis IDCP (3+4=7 or 3+5=8)****.
4 KudoZ points awarded for this answer.
Comment: "Muchísimas gracias"
35 mins
Erzsébet Czopyk
Hungary
Hungary
Specializes in field
Hungary
sworn translator, linguist, DPO
Native in: Hungarian (Variant: Hungary) 
Works in: Russian to Hungarian, Hungarian to Russian, Latvian to Russian, and 10 more.
Related KudoZ points
:
28
typo: necrosis coledociana / Choledochal necrosis (choledochal=biliary tract)
Clínica. Está íntimamente relacionada con la aparición precoz o tardía de la complicación. Así, en las formas precoces suele existir un deterioro brusco y progresivo de la función hepática, sobre todo, de los parámetros de coagulación tras unos días de funcionamiento normal del injerto. Este fracaso hepático fulminante conduce a la muerte del paciente si no se realiza un retrasplante urgente13. Por el contrario, en las formas tardías predominan las manifestaciones biliares, en forma de fístula biliar o biloma secundarias a necrosis coledociana, o bien una ictericia obstructiva progresiva debida a estenosis del árbol biliar intrahepático
https://www.elsevier.es/es-revista-cirugia-espanola-36-artic...
Consejo Consultivo de La Rioja
https://www.ccrioja.es › ... PDF
apreció una pancreatitis aguda con una necrosis coledociana. 9°. La solución que le dieron a este problema es adecuada (y muy eficaz).
Perineural invasion of cancer: a complex crosstalk between ...
https://www.ncbi.nlm.nih.gov › articles › PMC6356921
by SH Chen · 2019 · Cited by 113 — Perineural invasion (PNI) can be found in a variety of malignant tumors. It is a sign of tumor metastasis and invasion and portends the poor ...
Intraductal carcinoma is not assigned a Gleason grade (Epstein et al. 2016c). Intraductal carcinoma is linked to aggressive prostate cancer, as assessed by both pathologic and clinical outcome endpoints. It is usually associated with high-grade and high-volume carcinoma with a median Gleason score of 8 and T3 pathologic stage, with increased risk of extraprostatic extension, seminal vesicle invasion, and pelvic lymph node metastases (Robinson and Epstein 2010; Divatia and Ro 2016). The presence of intraductal carcinoma in needle biopsy tissue and transurethral resections is an independent indicator of early biochemical relapse and metastatic failure rate after radiation therapy (van der Kwast et al. 2012)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629988/
How is the Gleason Score Derived?
The pathologist looking at the biopsy sample will assign one Gleason grade to the most predominant pattern in your biopsy and a second Gleason grade to the second most predominant pattern. For example: 3 + 4. The two grades will then be added together to determine your Gleason score. Theoretically, Gleason scores range from 2-10. However, since Dr. Gleason’s original classification, pathologists almost never assign scores 2-5, and Gleason scores assigned will range from 6 to 10, with 6 being the lowest grade cancer.
What Does it Mean?
A Gleason score of 6 is low grade, 7 is intermediate grade, and a score of 8 to 10 is high grade cancer.
https://www.pcf.org/about-prostate-cancer/diagnosis-staging-...
https://www.cancer.net/cancer-types/prostate-cancer/stages-a...
https://www.pcf.org/about-prostate-cancer/diagnosis-staging-...
In memoriam Dr. Csákány M. György
https://www.elsevier.es/es-revista-cirugia-espanola-36-artic...
Consejo Consultivo de La Rioja
https://www.ccrioja.es › ... PDF
apreció una pancreatitis aguda con una necrosis coledociana. 9°. La solución que le dieron a este problema es adecuada (y muy eficaz).
Perineural invasion of cancer: a complex crosstalk between ...
https://www.ncbi.nlm.nih.gov › articles › PMC6356921
by SH Chen · 2019 · Cited by 113 — Perineural invasion (PNI) can be found in a variety of malignant tumors. It is a sign of tumor metastasis and invasion and portends the poor ...
Intraductal carcinoma is not assigned a Gleason grade (Epstein et al. 2016c). Intraductal carcinoma is linked to aggressive prostate cancer, as assessed by both pathologic and clinical outcome endpoints. It is usually associated with high-grade and high-volume carcinoma with a median Gleason score of 8 and T3 pathologic stage, with increased risk of extraprostatic extension, seminal vesicle invasion, and pelvic lymph node metastases (Robinson and Epstein 2010; Divatia and Ro 2016). The presence of intraductal carcinoma in needle biopsy tissue and transurethral resections is an independent indicator of early biochemical relapse and metastatic failure rate after radiation therapy (van der Kwast et al. 2012)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629988/
How is the Gleason Score Derived?
The pathologist looking at the biopsy sample will assign one Gleason grade to the most predominant pattern in your biopsy and a second Gleason grade to the second most predominant pattern. For example: 3 + 4. The two grades will then be added together to determine your Gleason score. Theoretically, Gleason scores range from 2-10. However, since Dr. Gleason’s original classification, pathologists almost never assign scores 2-5, and Gleason scores assigned will range from 6 to 10, with 6 being the lowest grade cancer.
What Does it Mean?
A Gleason score of 6 is low grade, 7 is intermediate grade, and a score of 8 to 10 is high grade cancer.
https://www.pcf.org/about-prostate-cancer/diagnosis-staging-...
https://www.cancer.net/cancer-types/prostate-cancer/stages-a...
https://www.pcf.org/about-prostate-cancer/diagnosis-staging-...
In memoriam Dr. Csákány M. György
Peer comment(s):
| neutral |
Muriel Vasconcellos
: You convinced me that your answer is correct, but no Spanish should appear because it will be filed incorrectly in the glossary. You could hide it and transpose the info to another answer.
28 mins
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Dear Muriel, I can edit the glossary entry if my answer will be suppoerted and accepted, but if I do not delete that part no one will know that this is a typo, so what you want me exactly to do?
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| neutral |
liz askew
: hmm, how about "comedo necrosis/comedonecrosis??see:https://www.oncotarget.com/article/24515/text/
1 hr
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I don't think so because of the grade :( sad for him... your link "Prostate cancer with comedonecrosis is frequently, but not exclusively, intraductal carcinoma
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Reference comments
1 hr
Reference:
see
Linfomas cutáneos primarios - PDF Free Download - DocPlayer
https://docplayer.es › 19812088-Linf...
·
Translate this page
Se distingue de otras en que no clasifica; las neoplasias no están agrupadas en categorías de ... Micosis fungoide folicular, comedoniana y quística.
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Note added at 1 hr (2022-11-06 22:57:13 GMT)
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Tumor Cell Anaplasia and Multinucleation Are Predictors of ...
https://www.ncbi.nlm.nih.gov › articles › PMC3925618
by JS Lewis Jr · 2012 · Cited by 38 — Anaplasia was defined as any ×40 field with ≥ 3 tumor nuclei with ... Comedo-type necrosis and brisk mitotic activity are usually present.
Dedifferentiation in adenoid cystic carcinoma - PMC - NCBI
https://www.ncbi.nlm.nih.gov › articles › PMC3927361
by RM Bavle · 2013 · Cited by 10 — ... cords of anaplastic cells, atypical mitoses, comedo necrosis and neoplastic cells with hyperchromatic and vesicular nuclei having multiple nucleoli.
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Note added at 1 hr (2022-11-06 22:58:42 GMT)
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Necrosis (areas of dead or dying cancer cells) is also noted. If there is necrosis, it means the tumor is growing quickly. The term comedo necrosis may be used if a breast duct is filled with dead and dying cells. Comedo necrosis is often linked to a high grade of DCIS and has a higher chance of developing into invasive breast cancer.
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Note added at 1 hr (2022-11-06 22:59:28 GMT)
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The 2019 International Society of Urological Pathology ...
https://www.urotoday.com › prostate-cancer › 122318-t...
16 Jul 2020 — Thus, for instance, intraductal carcinoma with comedo necrosis will be graded as Gleason grade 5 and incorporated in the Gleason score of ...
https://docplayer.es › 19812088-Linf...
·
Translate this page
Se distingue de otras en que no clasifica; las neoplasias no están agrupadas en categorías de ... Micosis fungoide folicular, comedoniana y quística.
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Note added at 1 hr (2022-11-06 22:57:13 GMT)
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Tumor Cell Anaplasia and Multinucleation Are Predictors of ...
https://www.ncbi.nlm.nih.gov › articles › PMC3925618
by JS Lewis Jr · 2012 · Cited by 38 — Anaplasia was defined as any ×40 field with ≥ 3 tumor nuclei with ... Comedo-type necrosis and brisk mitotic activity are usually present.
Dedifferentiation in adenoid cystic carcinoma - PMC - NCBI
https://www.ncbi.nlm.nih.gov › articles › PMC3927361
by RM Bavle · 2013 · Cited by 10 — ... cords of anaplastic cells, atypical mitoses, comedo necrosis and neoplastic cells with hyperchromatic and vesicular nuclei having multiple nucleoli.
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Note added at 1 hr (2022-11-06 22:58:42 GMT)
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Necrosis (areas of dead or dying cancer cells) is also noted. If there is necrosis, it means the tumor is growing quickly. The term comedo necrosis may be used if a breast duct is filled with dead and dying cells. Comedo necrosis is often linked to a high grade of DCIS and has a higher chance of developing into invasive breast cancer.
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Note added at 1 hr (2022-11-06 22:59:28 GMT)
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The 2019 International Society of Urological Pathology ...
https://www.urotoday.com › prostate-cancer › 122318-t...
16 Jul 2020 — Thus, for instance, intraductal carcinoma with comedo necrosis will be graded as Gleason grade 5 and incorporated in the Gleason score of ...
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