Glossary entry

English term or phrase:

T cell engaging antibody construct

French translation:

Une construction d\'anticorps qui recrute les lymphocytes T

Added to glossary by Maryse Larousse
Nov 6, 2015 10:52
8 yrs ago
4 viewers *
English term

T cell engaging antibody construct

English to French Medical Medical: Pharmaceuticals leukemia
The treatment of Philadelphia chromosome-negative relapsed / refractory
B-cell precursor acute lymphoblastic leukemia (Ph- ALL)
Product X is a CD19/CD3 bi-specific T cell engaging antibody construct.
It binds both the CD 19 receptor on cancer cells and the CD3 receptor on T cells to allow the patients-own T cells to target malignant cells.

Discussion

PLR TRADUZIO (X) Nov 6, 2015:
recruter: to recruit
engager: to engage
deux significations différentes
orgogozo Nov 6, 2015:
Possibilité : un anticorps chimérique bispécifique lCD19/CD3 recrutant les lymphocytes T. (SGDG...)

Proposed translations

+1
44 mins
Selected

Une construction d'anticorps qui recrute les lymphocytes T

Un anticorps chimerique associant deux domaines ciblant les lymphocytes T et les cellules cancéreuses
Peer comment(s):

agree François Begon
1 hr
neutral PLR TRADUZIO (X) : not to recruit, but to engage
1 hr
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Merci"
1 hr

.....est une construction d'anticorps qui engage les lymphocytes T

[PDF]Caractérisation de la mort cellulaire induite par un anticorps ...
https://tel.archives-ouvertes.fr/tel-00870033/document
de D Goéré - ‎2013 - ‎Autres articles
4 oct. 2013 - anticorps bi-spécifiques capables d'engager d'auttres effecteurs ...... dirigé, le MT110, a été étudiée in vitro et ex vivo sur des lignées cellulaires.
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